中文名称:非戈替尼
中文别名:菲格替尼
CAS No:1206161-97-8
分子式:C21H23N5O3S
折射率:1.748
密度:1.51±0.1 g/cm3(Predicted)
用途:1、一种高效、选择性的JAK1抑制剂,能够有效抑制JAK1、JAK2、JAK3和TYK2的活性，IC50值分别为10nM、28nM、810nM和116nM。Filgotinib is a potent and selective JAK1 inhibitor. It is considered a promising agent as it inhibits JAK1 selectively. Filgotinib displayed a selectivity of 30-fold for JAK1- over JAK2-d..